I'm reading a memoir by a man who went to Dharamsala seeking truth: TURTLE FEET by Nikolai Gronzi. He states what I think are supposed to be the Four Noble Truths in a way I hadn't heard before and that seems more accurate to me: "that all compounds are impermanent; that all physical and mental states, born out of a misconception about the ultimate way of things, are in the nature of suffering; that all phenomena are devoid of objective reality; and that Nirvana is peace."
I guess this seems more accurate to me because these days it's becoming clearer that suffering comes from the whole human apparatus of consciousness; not just from some mistaken view, but from the way the human psyche functions. That is to say, the mind solidifies everything and places it outside of itself, and also tends to make things permanent when nothing lasts more than an instant. So loss is a permanent feature of life as a human being, not because "things" die but because we imagine they were ever solid in the first place.
All of this perhaps sounds intellectual, but I think it does reflect the realization that happens when all of this gets seen through.